Amit Kumar Das

This study characterizes the regulatory role of the N-terminal β-flap in Staphylococcal thiol peroxidase (SaTpx) through structural and functional analysis, revealing its role in stabilizing the catalytic triad.

This study presents cryo-EM structures of mycobacterial Ku (mKu) in complex with DNA, revealing its role in NHEJ synapsis and identifying key residues for DNA binding and synaptic assembly.

The paper identifies D-Alanine-D-Alanine ligase (DdlB) as a potential drug target for Burkholderia pseudomallei using molecular docking and dynamics simulations, showing Conivaptan inhibits DdlB effectively.

This paper designs a multi-epitope vaccine against Burkholderia pseudomallei using in-silico and immunoinformatics methods, showing it is non-toxic, non-allergic, and immunogenic.

This study designs a scaffold-based multiepitope vaccine against tuberculosis by engineering the Ag85A protein to enhance stability and antigenicity through computational methods.

This paper introduces a fast and robust method to identify drug response biomarkers and stratify samples, using transcriptomics data and Bayesian network analysis.