Chikoo Oosawa

This paper evaluates the accuracy of zero-dimensional projections in biological systems by analyzing information loss and risk metrics across different models and conditions.

The paper introduces a covariant hierarchy of descriptors (cBST1-cBST3) for biochemical systems and validates their effectiveness in reducing error in log-rate approximations.

This study uses giant Dictyostelium cells to reveal directional cAMP signaling and coordinated Ca2+ responses, showing spatially structured intracellular signaling aligned with cellular polarity.