Cell BiologybioRxivPreprint
A genetic and physiological model of renal dysfunction in Lowe syndrome
Navyashree A Ramesh, Vaishali Kataria, Indra Sara Lama…·Padinjat Raghu
This study uses a Drosophila nephrocyte model to show that OCRL loss causes endolysosomal defects and kidney dysfunction, which can be rescued by human OCRL but not by mutant variants.
3 citations