Author

Llywelyn Griffith

King's College LondonORCID 0009-0008-0223-8895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:metagenomics· 1

Frequent Co-Authors

Ian M. SudberyiD· 2 shared Jernej UleiD· 2 shared Stuart A. WilsoniD· 2 shared Almaz Huseynova· 1 shared Anca M. FarcasiD· 1 shared André T. LopesiD· 1 shared Ang LiiD· 1 shared Anob M. ChakrabartiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Ian M. SudberyORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 29, 2026

CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development

Simeon R. Mihaylov, André T. Lopes, Margaux Silvestre…·Sila K. Ultanir

This study identifies CDKL5 as a kinase that phosphorylates nELAVL proteins, enhancing mRNA binding and protein synthesis, and shows its role in visual cortex development.

DOI 10.64898/2026.04.07.716766

mouseproteomics

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Molecular BiologybioRxivPreprintMar 6, 2025

PRMT activity promotes global 3' UTR shortening in proliferating cells

Llywelyn Griffith, Charlotte Capitanchik, Shaun Moore…·Jernej Ule

This study shows PRMT activity regulates 3' UTR shortening in proliferating cells through alternative polyadenylation, impacting cancer and immune-related diseases.

DOI 10.1101/2025.03.06.641848

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJul 22, 2023

hnRNPUL1 ensures efficient Integrator-mediated cleavage of snRNAs and is mutated in amyotrophic lateral sclerosis

Ivaylo D Yonchev, Carmen V. Apostol, Llywelyn Griffith…·Stuart A. Wilson

This study identifies hnRNPUL1's role in Integrator-mediated snRNA cleavage and links its mutations to amyotrophic lateral sclerosis.

4 citations

humanmultiome

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Molecular BiologyMolecular CellPeer-reviewedMay 16, 2019

Co-transcriptional loading of RNA export factors shapes the human transcriptome.

Nicolas Viphakone, Ian M. Sudbery, Llywelyn Griffith…·Stuart A. Wilson

The paper shows that RNA export factors are co-transcriptionally recruited to mRNAs via splicing before 3-end processing, influencing splicing and polyadenylation.

141 citationstop 3%

humanbulk RNA-seq

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