Author
Wellcome Sanger InstituteORCID 0009-0008-1799-5776Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Magdalena E Strauß, Andrew J. Waters, Holly Roberston…·D. Adams
Saturation-seq combines genome editing and single-cell RNA-seq to quantify variant effects on NFE2L2, accurately distinguishing pathogenic from benign variants.
Erica Bello, Kathleen R. Long, Sho Iwama…·Andrew Roger Bassett
The paper validates an Alzheimer's disease-associated SNP in PTK2B that alters microglial function through changes in chromatin accessibility and gene expression.
Claudia Feng, Elin Madli Peets, Yan Zhou…·Britta Velten
The paper presents a genome-scale CRISPRi perturbation map in human pluripotent stem cells using single-cell RNA sequencing to study trans gene regulation across diverse genetic backgrounds.