Dominique R. Smith

This paper introduces TensionDL, a deep learning model that predicts pN receptor tension maps from cell morphology and vinculin images, validated across cell types and substrate stiffnesses.

This study measures piconewton forces transmitted by CARs during antigen engagement, showing co-stimulatory domains are essential for force generation and early signaling.

The paper investigates how ComI, a transmembrane peptide in Bacillus subtilis, inhibits transformation by selectively killing competent cells through permeabilization.