Author

Kaela O’Connor

University of OttawaORCID 0009-0008-5784-2619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Organism:human· 1

Frequent Co-Authors

Sally SpendiffiD· 2 shared Adelaide Maria Fernandes Borralho· 1 shared Alain Geille· 1 shared Albert Carbonell· 1 shared Alessandro PrigioneiD· 1 shared Alex Garanto· 1 shared Alex Mackenzie· 1 shared Anastasia KritharaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Sally SpendiffORCID

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2 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedMay 7, 2026

KG-Bench: Benchmarking Graph Neural Network Algorithms for Drug Repurposing

Siqi Wei, Christo Sasi, Jelle Piepenbrock…·Sara Pintado

KG-Bench benchmarks graph neural networks for drug repurposing using the Open Targets dataset, finding TransformerConv achieves the highest performance.

DOI 10.1093/bioinformatics/btag159

graph neural networkbenchmarking

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 31, 2025

Cell-type-specific adaptations to mitochondrial stress underly the neurological presentations of MTRFR mutations

Mariana Zarate-Mendez, Kaela O’Connor, Natalia Malig…·Rita Horváth

This study identifies cell-type-specific adaptations to mitochondrial stress in MTRFR mutations, showing cortical neurons activate survival programs while motor neurons undergo apoptosis.

DOI 10.64898/2025.12.30.696998

humanbulk RNA-seq

𝕏 PostBluesky