Yuhsin Vivian Huang

The paper describes the generation of an iPSC line from a patient with immune checkpoint inhibitor-induced myocarditis and type I diabetes, highlighting its pluripotency and potential for studying disease mechanisms.

The paper generates three iPSC lines from an ICIM patient and controls to study disease mechanisms and develop therapies.

This study identifies CXCR3-CXCL9/10 axis as a therapeutic target for ICI-mediated myocarditis using mouse models and human patient data.