Ruth Verstraten

The paper uses nanopore sequencing to show herpesvirus mRNAs have longer poly(A) tails than cellular or other viral transcripts, suggesting a unique mechanism for enhancing gene expression.

This paper introduces DRAP3R, a method for analyzing Pol III transcribed RNAs and their modifications, revealing new transcripts and epitranscriptomic changes in infected cells.

The paper evaluates Dorado basecalling for nanopore DRS to detect m6A modifications in RNA, finding that stringent filtering improves accuracy and revealing cell-type differences in m6A proportions at conserved sites.

The paper develops a novel method for high-resolution transcriptome annotation from Nanopore DRS data, demonstrating its effectiveness on both synthetic and real datasets, including a new annotation of human adenovirus type F 41.