Author

Dan Lou

German Cancer Research CenterORCID 0009-0008-6154-1341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel Kirrmaier· 3 shared Michael KnopiD· 3 shared Konrad HerbstiD· 2 shared Krisztina GubiczaiD· 2 shared Lars Michael SteinmetziD· 2 shared Matthias MeureriD· 2 shared Melanie KrauseiD· 2 shared Shengdi LiiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioengineering

Daniel Kirrmaier

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 10, 2026

A Modular Chromosomally Integrated Yeast Surface Display Platform for Quantitative Serology and Immune Profiling

Dan Lou, Hans Hombauer, Florian Huber…·Michael Knop

This paper introduces a chromosomally integrated yeast surface display system for scalable, quantitative antibody profiling and serological assays.

DOI 10.64898/2026.09.08.750026

yeastproteomics

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Cell BiologybioRxivPreprintAug 7, 2026

Cell organization and disturbance-mapping using image activated cell-profiling (CODIAC)

Melanie Krause, Dan Lou, Shengdi Li…·Lars Michael Steinmetz

CODIAC profiles spatial protein localization and abundance changes using image-enabled sorting and machine learning, detecting perturbation effects on the spatial proteome.

DOI 10.64898/2026.08.06.742695

imagingdeep learning

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Molecular BiologybioRxivPreprintDec 16, 2025

Improved cloning-free one-step CRISPR-Cas12a-assisted tagging of mammalian genes using PCR generated reagents (PCR tagging)

Dan Lou, Daniel Kirrmaier, Melanie Krause…·Michael Knop

The paper improves CRISPR-Cas12a-assisted gene tagging in mammalian cells by enhancing HDR efficiency and reducing off-target integrations through modified cassettes and repair pathway modulation.

1 citation

humanCRISPR screen

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