Author

Krisztina Gubicza

Heidelberg UniversityORCID 0000-0002-4591-8697Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Dan LouiD· 2 shared Daniel Kirrmaier· 2 shared Lars Michael SteinmetziD· 2 shared Melanie KrauseiD· 2 shared Michael KnopiD· 2 shared Shengdi LiiD· 2 shared Daniel SchraivogeliD· 1 shared Haeyeon Jung· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Dan LouORCID

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2 papers

Recent·Most cited

Cell organization and disturbance-mapping using image activated cell-profiling (CODIAC)

Melanie Krause, Dan Lou, Shengdi Li, Haeyeon Jung, Daniel Kirrmaier, Krisztina Gubicza, Daniel Schraivogel, Michael Knop, Lars Michael Steinmetz

CODIAC profiles spatial protein localization and abundance changes using image-enabled sorting and machine learning, detecting perturbation effects on the spatial proteome.

bioRxiv · Aug 7, 2026 · PreprintCell Biology

Improved cloning-free one-step CRISPR-Cas12a-assisted tagging of mammalian genes using PCR generated reagents (PCR tagging)

Dan Lou, Daniel Kirrmaier, Melanie Krause, Shengdi Li, Krisztina Gubicza, Konrad Herbst, Matthias Meurer, V. Talya Yerlici, Omar Wagih, Lars Michael Steinmetz, Michael Knop

The paper improves CRISPR-Cas12a-assisted gene tagging in mammalian cells by enhancing HDR efficiency and reducing off-target integrations through modified cassettes and repair pathway modulation.

bioRxiv · Dec 16, 2025 · PreprintMolecular Biology