Author

Emanuel Lange

Bielefeld UniversityORCID 0009-0008-6620-6681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:software / tool· 2 Approach:benchmark study· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Robert HeyeriD· 3 shared Alejandro Benjamin Reyes SantamariaiD· 1 shared Benjamin SaalfeldiD· 1 shared Daniel WalkeiD· 1 shared Dirk BenndorfiD· 1 shared Jacob KrügeriD· 1 shared Kay SchallertiD· 1 shared Petra LutteriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersSystems Biology

Robert HeyerORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintJun 30, 2026

✦ In-depth digest

Curating MitoCore: A Standardized Small-Scale Human Metabolic Model as Platform for Proteomics Integration and Disease Modeling

Emanuel Lange, Alejandro Benjamin Reyes Santamaria, Robert Heyer

Re-annotated MitoCore (SBML3, UniProt, EC, Human-GEM gene rules) supports sMOMENT proteomics integration, reducing thrombocyte ATP prediction error by 89% relative to the original model.

DOI 10.64898/2026.06.29.734258

humanproteomics

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Systems BiologybioRxivPreprintOct 28, 2025

A structured evaluation and benchmarking of Boolean logical modelling tools

Benjamin Saalfeld, Emanuel Lange, Jacob Krüger…·Robert Heyer

This paper evaluates 20 Boolean modelling tools for signal transduction and gene regulatory networks using FAIR4RS and usability criteria, finding significant variation in functionality and simulation capabilities.

1 citation

benchmark studybenchmarking

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BioinformaticsInternational Journal of Molecular SciencesPeer-reviewedOct 12, 2021

MPA_Pathway_Tool: User-friendly, automatic assignment of microbial community data on metabolic pathways

Daniel Walke, Kay Schallert, Prasanna Ramesh…·Robert Heyer

The paper introduces a user-friendly web tool for assigning microbial community data to metabolic pathways, enabling pathway creation and automated data mapping.

7 citations

metagenomicsexperimental assay

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