NeurosciencebioRxiv
A role for LGI1 in regulating pain sensitivity.
Adham Farah, Ryan Patel, Piotr Popławski…·John M. Dawes
This study investigates the role of LGI1 in pain regulation using mouse models, finding that LGI1 ablation in spinal neurons exacerbates neuropathic pain behaviors, suggesting a spinal mechanism for its role in pain sensitivity.
DOI 10.1093/brain/awae302