Hanns Ulrich Zeilhofer

This study identifies Tmem117 as an oligodendrocyte-enriched regulator of NCX activity, linking myelin homeostasis to counterregulatory response and metabolic health.

This study shows nerve injury shifts spinal circuit recruitment from inhibitory to excitatory parvalbumin interneurons, causing mechanical allodynia.

The paper identifies distinct neural ensembles in mouse spinal cord encoding mechanical and heat pain and shows their role in affective pain behavior.

This study investigates the role of LGI1 in pain regulation using mouse models, finding that LGI1 ablation in spinal neurons exacerbates neuropathic pain behaviors, suggesting a spinal mechanism for its role in pain sensitivity.

The paper identifies a GABAergic pathway from the RVM to the spinal dorsal horn that mediates bilateral antinociception and is involved in pain control.

The paper identifies two functionally distinct serotonergic neuron populations in the hindbrain that have opposing effects on nociception by targeting different spinal regions.

This study characterizes the molecular changes in the mouse hippocampus during the acute stress response using multiomic profiling and identifies rapid resolution of molecular events within 4 hours.

The paper identifies CCK+ S1-CST neurons as a major cortical input to the spinal dorsal horn and characterizes their synaptic connections and molecular diversity.

The paper uses TRAP to analyze translatomes of excitatory and inhibitory neurons in mouse spinal cords, finding neuropeptide genes associated with modality-specific processing and showing little translatome change in neuropathic pain.

The paper introduces mesoSPIM, an open-source light-sheet microscope initiative for imaging large cleared tissue samples with near-isotropic resolution.