Author

Xinyun Jiang

Johns Hopkins UniversityORCID 0009-0008-7388-8369Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Research Focus:protein design· 1

Frequent Co-Authors

Denis WirtziD· 2 shared Eban A. HannaiD· 2 shared Vasco QueirogaiD· 2 shared Alice AmitranoiD· 1 shared André ForjaziD· 1 shared Bryce Lloyd· 1 shared Cai Zhou· 1 shared Cameron MyhrvoldiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Denis WirtzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 25, 2026

Reprogramming CAR-T cell function through synthetic cytokine receptors suppresses metastatic progression of TNBC

Eban A. Hanna, Alice Amitrano, André Forjaz…·Denis Wirtz

This study enhances CAR-T cell migration through synthetic cytokine receptors, reducing metastasis in TNBC mouse models.

DOI 10.64898/2026.10.22.760671

mouseexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintOct 16, 2026

Protein Deimmunization with a Generative Diffusion Model

Zijie Chen, Chih-chieh Yu, Cai Zhou…·Kaiyi Jiang

The paper introduces MESSI, a generative diffusion model for deimmunizing proteins by designing sequences with minimal immunogenicity while preserving structure and function.

DOI 10.64898/2026.10.09.758136

protein sequencediffusion model

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BioengineeringbioRxivPreprintOct 5, 2025

Optimization of velocity receptor transduction in CAR T cells

Xinyun Jiang, Vasco Queiroga, Eban A. Hanna, Denis Wirtz

This study optimizes velocity receptor (VR) transduction in CAR T cells by evaluating vector modifications and transduction efficiency, finding that VR5IL8 and VR5TNF perform best.

DOI 10.1101/2025.10.05.680548

mousestatistical model

𝕏 PostBluesky