Author

Isabel Soto

University of North Texas Health Science CenterORCID 0009-0008-7763-0437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:rat· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 1

Frequent Co-Authors

Michael F. SalvatoreiD· 4 shared Vicki A. NejtekiD· 4 shared Robert McManusiD· 3 shared Walter Navarrete· 3 shared Ella Anle Kasanga· 2 shared Isha Mhatre‐WintersiD· 2 shared Jason R. RichardsoniD· 2 shared Kirby Doshier· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersNeuroscience

Michael F. SalvatoreORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 20, 2026

Serum UCHL1, GFAP, and NfL track tyrosine hydroxylase loss in substantia nigra in two Rat Models of Parkinsons Disease

Isabel Soto, Robert McManus, Walter Navarrete…·Michael F. Salvatore

1 citation

𝕏 PostBluesky

NeuroscienceExperimental NeurologyPeer-reviewedJun 27, 2024

Moderate intensity aerobic exercise in 6-OHDA-lesioned rats alleviates established motor deficits and reduces neurofilament light and glial fibrillary acidic protein serum levels without increased striatal dopamine or tyrosine hydroxylase protein

Ella Anle Kasanga, Isabel Soto, Ashley Centner…·Michael F. Salvatore

This study shows moderate intensity aerobic exercise improves motor deficits and reduces blood biomarkers in a Parkinson's rat model without increasing striatal dopamine or tyrosine hydroxylase.

14 citations

ratexperimental assay

𝕏 PostBluesky

NeuroscienceExperimental NeurologyPeer-reviewedJun 1, 2024

Aging hastens locomotor decline in PINK1 knockout rats in association with decreased nigral, but not striatal, dopamine and tyrosine hydroxylase expression

Isabel Soto, Robert McManus, Walter Navarrete…·Michael F. Salvatore

The paper evaluates aging's effect on motor and cognitive impairments in PINK1 knockout rats, finding decreased nigral dopamine and tyrosine hydroxylase with age, but not in striatum.

7 citations

𝕏 PostBluesky

NeuroscienceFrontiers in NeurosciencePeer-reviewedMay 16, 2024

PINK1 knockout rats show premotor cognitive deficits measured through a complex maze

Isabel Soto, Vicki A. Nejtek, David Peter Siderovski, Michael F. Salvatore

The paper tests cognitive deficits in PINK1 knockout rats using a modified T-maze, finding increased errors and slower performance compared to wild-type rats.

7 citations

ratexperimental assay

𝕏 PostBluesky