Jason R. Richardson

This study shows that prolonged low-dose inhalation of paraquat in mice causes male-specific dopaminergic neuron loss and motor deficits, linking it to Parkinson's disease.

This study introduces a 3D Neuron-on-Chip platform to study neuronal injury responses in human prefrontal cortex neurons, revealing biphasic injury responses and stage-specific inflammatory signaling.

This study shows that microplastic exposure alters gut microbiome composition and serum metabolome in mice, with sex-specific and dose-dependent effects.

This study shows DDT exposure increases neuroinflammation in microglia, potentially contributing to Alzheimer's disease risk through direct effects on microglial function.

This study shows moderate intensity aerobic exercise improves motor deficits and reduces blood biomarkers in a Parkinson's rat model without increasing striatal dopamine or tyrosine hydroxylase.

This study examines changes in GDNF receptor expression in the striatum and substantia nigra following a nigrostriatal lesion in rats, finding differential expression patterns of GFR-1 and RET that may impact GDNF therapeutic efficacy.

The paper investigates how increased ser31 tyrosine hydroxylase phosphorylation in the substantia nigra compensates for dopamine loss and delays hypokinesia onset in a rat model of Parkinson's disease.