Ken J. Kron

This paper introduces REPRESS, a deep learning model that predicts cell-type-specific microRNA binding and mRNA degradation from RNA sequences, outperforming existing methods in multiple tasks.

The paper introduces BigRNA, an RNA foundation model that predicts RNA biology from DNA sequence and identifies therapeutic effects of SBOs on gene expression and splicing.

This study evaluates off-target effects of steric-blocking oligonucleotides using RNA-seq and finds that in silico methods have limited utility for predicting these effects.

This paper shows that the ATP7B variant c.1934T>G causes exon 6 skipping, leading to loss of function and confirming its pathogenicity in Wilson Disease.

The paper identifies driver genes in prostate cancer by analyzing convergence of non-coding mutations in regulatory regions using 3D chromatin interactions and genomic data.