Author

Yi-Hung Lee

University of California San DiegoORCID 0009-0009-1642-2367Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:contrastive learning· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Emily PaniD· 2 shared Prashant MaliiD· 2 shared Yesh DoctoriD· 2 shared Yifan Zhang· 2 shared Alina Sigaeva· 1 shared Amir DailamyiD· 1 shared Antoine ForgetiD· 1 shared Benjamin J. PolaccoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Emily PanORCID

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2 papers

Recent·Most cited

BioengineeringNature BiotechnologyPeer-reviewedJul 1, 2026

A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS

Sami Nourreddine, Yesh Doctor, Amir Dailamy…·Prashant Mali

The paper generates a CRISPRi perturbation cell atlas in human induced pluripotent stem cells, identifies novel regulators of pluripotency and metabolism, and proposes a machine learning framework for predicting perturbation recipes.

12 citationstop 1%

humanCRISPR screen

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Synthetic BiologybioRxivPreprintDec 23, 2025

Multiplexed Pan Soluble Ligandome Assaying via OASIS

Yi-Hung Lee, Yesh Doctor, Yifan Zhang…·Prashant Mali

The paper introduces OASIS, a method to screen soluble ligands by enforcing autocrine signaling, and applies it to identify self-renewal factors in hiPSCs.

DOI 10.64898/2025.12.21.695830

humanproteomics

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