Author

Daniel S Brush

University of WashingtonORCID 0009-0009-2046-4973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Gayani K. PereraiD· 1 shared Dustin J. MalyiD· 1 shared Ethan G. Stoddard· 1 shared Jessica J. SimoniD· 1 shared Linglan FangiD· 1 shared Martin G. GolkowskiiD· 1 shared Yuhao Zhong· 1 shared Zachary E. PotteriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

B. Gayani K. PereraORCID

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1 paper

Recent·Most cited

Cell BiologyNature Chemical BiologyPeer-reviewedMay 12, 2026

Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

Ethan G. Stoddard, B. Gayani K. Perera, Linglan Fang…·Dustin J. Maly

This study identifies how Raf inhibitor potency varies with Raf activity and shows that cobimetinib enhances sensitivity to DFG-out inhibitors by disrupting autoinhibited Raf-Mek complexes.

3 citationstop 5%

humanbulk RNA-seq

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