Jacob D. Sternbach

The paper uses proteomics to compare alterations in the right atrium and right ventricle of pigs with right heart failure, identifying shared and distinct metabolic changes.

This study uses multi-omics profiling to identify molecular mechanisms contributing to progressive right ventricular dysfunction in pigs.

This study identifies ER-mitochondrial dysfunction and inflammatory macrophages as drivers of right atrial dysfunction using multi-omic analyses in a pulmonary artery banded swine model.

SC144 improves right ventricular function in pulmonary artery banded pigs by reducing inflammation, restoring metabolism, and enhancing cell communication.