Zhichang Yang

This study identifies tissue retention of mature dendritic cells as a driver of age-associated protective tolerogenic lymphoid structures in mice and humans.

The paper develops nanoMAPS, a droplet-based magnetic affinity purification system for surfaceome profiling of 100-500 cells, improving recovery and reducing non-specific absorption.

This study identifies how ataxin-2 reduction promotes neuroprotection by activating metabolic programs in neurons and astrocytes, enhancing energy production and trophic support.