Author

Amanda C. Lorentzian

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aditya A. AnandiD· 1 shared Alan G. GutierreziD· 1 shared Anthony C. AntonelliiD· 1 shared Anugraha R. RajagopalaniD· 1 shared Caleb K. ChaniD· 1 shared Camille-Charlotte BalançaiD· 1 shared Catherine B. CarboneiD· 1 shared Christine MoussioniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Aditya A. AnandORCID

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Author profile →

2 papers

Recent·Most cited

Cell-Type-Specific Surfaceome Profiling of 100-500 Isolated Cells using a Droplet-Based Magnetic Affinity Purification System

Amanda C. Lorentzian, Juliet M. Bartleson, Terence Ho, Hao Xu, Christopher B. Bullock, Zhichang Yang, Alan G. Gutierrez, Meena Choi, Tommy K. Cheung, Christopher M. Rose, Hua Zhang, William T. Yewdell, Ying Zhu

The paper develops nanoMAPS, a droplet-based magnetic affinity purification system for surfaceome profiling of 100-500 cells, improving recovery and reducing non-specific absorption.

Nature Communications · Sep 18, 2026Peer-reviewedSystems Biology

Intratumoral cDC1-T Cell Clusters Serve as Sites of Local Costimulation to Enhance CTL-Mediated Tumor Rejection

Catherine B. Carbone, Markus K. Brown, Camille-Charlotte Balança, Anthony C. Antonelli, Shiuh-Ming Luoh, Karl L. Banta, Vincent Rouilly, Ximo Pechuan-Jorge, Guadalupe Ortiz-Muñoz, Jeanne Cheung, Inés Marín, Ellen Duong, Aditya A. Anand, Caleb K. Chan, Anugraha R. Rajagopalan, , Christine Moussion

This study identifies spatially organized cDC1-T cell clusters within tumors as critical for enhancing CTL-mediated tumor rejection through local costimulation.

bioRxiv · May 19, 2025 · PreprintImmunology