Author

Christine Moussion

GenentechORCID 0000-0002-1641-4094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Inés MaríniD· 3 shared Anugraha R. RajagopalaniD· 2 shared Jérémie DecalfiD· 2 shared Jian Wei JiangiD· 2 shared Kathryn Geiger-SchulleriD· 2 shared Sandra RostiD· 2 shared Shannon J. TurleyiD· 2 shared Abishek Balachandra VaidyaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Inés MarínORCID

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Author profile →

5 papers

Recent·Most cited

Tissue retention of dendritic cells drives age-associated protective tolerogenic lymphoid structures

Inés Marín, Marcela Blanca Morales, Brian Orcutt-Jahns, Jessica Preston, Kevin Marroquín, Zhichang Yang, Ying Zhu, Joshua Webster, Christine Moussion

This study identifies tissue retention of mature dendritic cells as a driver of age-associated protective tolerogenic lymphoid structures in mice and humans.

bioRxiv · Oct 11, 2026 · PreprintImmunology

Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoidstructures in cancer

Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis, Jessica Le Bérichel, Pauline Hamon, László Halász, Abishek Balachandra Vaidya, Brian Y. Soong, Emir Radkevich, Hye Mi Kim, Matthew D. Park, Romain Donné, Leanna Troncoso, Rachel A. Kaplan, Clotilde Hennequin, , Miriam Mérad

This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.

Science · Jul 16, 2026Peer-reviewedImmunology

Fibroblastic FLT3L supports lymph node dendritic cells in the interfollicular niche

Sunny Z. Wu, Ryan S. Lane, Christopher Davidson, Ashley Byrne, Giulia Protti, Inés Marín, Endi K. Santosa, Alberto Guarnieri, Brandon D. Kayser, Hejin Huang, Katherine Williams, Matthew Fernandez, Jian Wei Jiang, Juan Zhang, Raymond Asuncion, , Shannon J. Turley

The paper identifies Grem1-expressing fibroblastic reticular cells as a source of FLT3L that supports dendritic cell homeostasis and function in lymph nodes.

Nature Immunology · Nov 17, 2025Peer-reviewedImmunology

Intratumoral cDC1-T Cell Clusters Serve as Sites of Local Costimulation to Enhance CTL-Mediated Tumor Rejection

Catherine B. Carbone, Markus K. Brown, Camille-Charlotte Balança, Anthony C. Antonelli, Shiuh-Ming Luoh, Karl L. Banta, Vincent Rouilly, Ximo Pechuan-Jorge, Guadalupe Ortiz-Muñoz, Jeanne Cheung, Inés Marín, Ellen Duong, Aditya A. Anand, Caleb K. Chan, Anugraha R. Rajagopalan, , Christine Moussion

This study identifies spatially organized cDC1-T cell clusters within tumors as critical for enhancing CTL-mediated tumor rejection through local costimulation.

bioRxiv · May 19, 2025 · PreprintImmunology

Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq

Kathryn Geiger-Schuller, Basak Eraslan, Olena Kuksenko, Kushal K. Dey, Karthik A. Jagadeesh, Pratiksha I. Thakore, Özge Karayel, Andrea R. Yung, Anugraha R. Rajagopalan, Ana M. Meireles, Karren Yang, Liat Amir-Zilberstein, Toni Marie Delorey, Devan Phillips, Raktima Raychowdhury, , Aviv Regev

The paper uses Perturb-seq to systematically study 1,130 E3 ligases and their roles in inflammatory responses in dendritic cells, revealing co-functional modules and genetic interactions.

bioRxiv · Jan 23, 2023 · PreprintGenomics