Author

Manali S. Phadke

Moffitt Cancer CenterORCID 0009-0009-4047-9304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Jay K. MandulaiD· 1 shared Jiannong LiiD· 1 shared Keiran S.M. SmalleyiD· 1 shared Lilit KarapetyaniD· 1 shared Paulo C. RodrígueziD· 1 shared Peter A. ForsythiD· 1 shared Y. Ann CheniD· 1 shared Zhihua CheniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Jay K. MandulaORCID

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1 paper

Recent·Most cited

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedDec 1, 2023

Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models

Manali S. Phadke, Jiannong Li, Zhihua Chen…·Keiran S.M. Smalley

This study investigates the mechanisms of action and resistance of anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma models, finding differential effects on CD4+ T cell polarization and CD8+ T cell function.

18 citations

mousebulk RNA-seq

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