Author

Peter A. Forsyth

Moffitt Cancer CenterORCID 0000-0002-3756-8594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Zhihua CheniD· 2 shared Brittany R. Evernden· 1 shared Fredrick L. Locke· 1 shared Gerald Wallace· 1 shared Hasan Alhaddad· 1 shared Inna SmalleyiD· 1 shared Jay K. MandulaiD· 1 shared Jiannong LiiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Zhihua ChenORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 18, 2023

Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease

Mariam Lotfy Khaled, Yuan Ren, Ronak Kundalia…·Inna Smalley

This study identifies branched-chain keto acid accumulation in leptomeningeal disease CSF, showing immune suppression and neurodegeneration, and shows that reducing BCKA improves outcomes in mouse models.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedDec 1, 2023

Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models

Manali S. Phadke, Jiannong Li, Zhihua Chen…·Keiran S.M. Smalley

This study investigates the mechanisms of action and resistance of anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma models, finding differential effects on CD4+ T cell polarization and CD8+ T cell function.

18 citations

mousebulk RNA-seq

𝕏 PostBluesky