Ryu F Williston

This study designs a peptidomimetic inhibitor that blocks Vibrio cholerae adhesin FrhA, showing nanomolar binding affinity and reduced biofilm formation.

This study uses cryo-ET and subtomogram averaging to determine the in situ architecture of the Tad pilus machine in Caulobacter crescentus, revealing its assembly intermediates and structural framework.

This paper develops a bacteria-mimetic bioadhesive using a Vibrio cholerae-derived peptide to achieve strong, non-covalent mucus adhesion and drug delivery.