Author
Vanderbilt University Medical CenterORCID 0009-0009-6399-9492Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Katie Colbert Coate, Jinhua Liu, Min Guo…·Roland W. Stein
This study shows that MAFB is essential for maintaining adult human α-cell identity and function, linking its downregulation to impaired glucagon secretion and mitochondrial dysfunction in diabetes.
Diane C. Saunders, Fan Feng, Alexander L. Hopkirk…·Marcela Briššová
The paper maps the morphological and functional maturation of human endocrine pancreas from birth to age 10 using pediatric tissue samples and imaging techniques.
Carmella Evans‐Molina, Yasminye D. Pettway, Diane C. Saunders…·Marcela Briššová
In 299 islet preparations from donors without diabetes, endocrine cell composition, not donor demographics, tracked insulin secretion, and δ cell percentage rose with type 2 diabetes genetic risk.
Shristi Shrestha, Diane C. Saunders, John T. Walker…·Marcela Briššová
The paper identifies combinatorial transcription factor expression in human islet cells and shows it correlates with functional maturity and electrophysiological activity.