Author

Andria Michael

University of CyprusORCID 0009-0009-8193-8423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Anna OnisiforouiD· 2 shared Morfeas KoumasiD· 2 shared Panos ZanosiD· 2 shared Elmar MammadoviD· 1 shared Polymnia GeorgiouiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersNeuroscience

Anna OnisiforouORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 4, 2025

Selective transcriptomic recovery by (2R,6R)-hydroxynorketamine in opioid-abstinent mice: Machine learning identifies predictive biomarkers

Anna Onisiforou, Morfeas Koumas, Andria Michael, Panos Zanos

This study uses machine learning to identify predictive biomarkers of (2R,6R)-HNK treatment response in opioid-abstinent mice, revealing gene expression changes and context-dependent therapeutic effects.

DOI 10.1101/2025.06.04.657935

mousebulk RNA-seq

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NeurosciencebioRxivPreprintDec 7, 2023

(2R,6R)-hydroxynorketamine facilitates extinction and prevents emotional impairment and stress-induced reinstatement in morphine abstinent mice

Andria Michael, Anna Onisiforou, Polymnia Georgiou…·Panos Zanos

This paper demonstrates that (2R,6R)-hydroxynorketamine reverses maladaptive behaviors and prevents relapse in morphine-abstinent mice by enhancing BDNF and GluN2A signaling.

1 citation

mouseexperimental assay

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