Developmental BiologybioRxivPreprint
Reduced Levels of Lagging Strand Polymerases Shape Stem Cell Chromatin
Jonathan C. Snedeker, Brendon E. M. Davis, Rajesh Ranjan…·Xin Chen
The paper shows that reduced levels of lagging strand polymerases in stem cells lead to asymmetric histone incorporation, which can be induced in progenitor cells through genetic or chemical manipulation.
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