Author

Fatima Hassan

Medizinische Hochschule HannoverORCID 0009-0009-8605-8580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alf HonigmanniD· 1 shared Andre KrausiD· 1 shared Andrea GrundiD· 1 shared Antonia IbeliD· 1 shared Bjoern BuchholziD· 1 shared Carlos Cordero· 1 shared Claudia Dafinger· 1 shared Dieter HaffneriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alf HonigmannORCID

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2 papers

Recent·Most cited

GeneticsMolecular TherapyPeer-reviewedAug 21, 2025

In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease

Antonia Ibel, Rishi Bhardwaj, Duygu Elif Yılmaz…·Michael M. Kaminski

This study shows that CRISPR base editing can correct pathogenic PKD1 variants in mice, reducing liver cysts and increasing polycystin-1 expression.

9 citationstop 3%

mouseexperimental assay

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Cell BiologybioRxivPreprintAug 8, 2025

The fibrocystin C-terminal domain inhibits Src/STAT3 signal induced cystogenesis of kidney epithelia.

Fatima Hassan, Susanne T. Hahnenstein, Andre Kraus…·Wolfgang H. Ziegler

This study shows that the fibrocystin C-terminal domain suppresses Src/STAT3 signaling, preventing cyst formation in kidney epithelial cells by inhibiting secretory phenotype and STAT3-dependent transcription.

DOI 10.1101/2025.08.08.669180

proteomicsexperimental assay

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