Author

Ethan T Holleman

University of California, DavisORCID 0009-0009-8621-1303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Frederic L. ChediniD· 2 shared Adam T. FishburniD· 1 shared Alice L. B. PyneiD· 1 shared Avery E. RobertsoniD· 1 shared Chase L. S. SkawinskiiD· 1 shared Cole J. FlorioiD· 1 shared Priya S. ShahiD· 1 shared Rees Sitchon· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Frederic L. ChedinORCID

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2 papers

Recent·Most cited

Molecular BiologyProtein SciencePeer-reviewedMay 15, 2026

Sequence and Structural Alignments Reveal Insights into ANKLE2 Evolution and Function

Adam T. Fishburn, Cole J. Florio, Chase L. S. Skawinski…·Priya S. Shah

The paper uses sequence and structural alignments to study ANKLE2 evolution and function, revealing conserved domains and potential roles in DNA damage response.

DOI 10.1002/pro.70618

humanprotein structure

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 24, 2025

Protein-mediated stabilization and nicking of the non-template DNA strand dramatically affect R-loop formation in vitro

Ethan T Holleman, Thomas E. Catley, Tadas Sereiva…·Frederic L. Chedin

This study shows that DNA-binding proteins and nicks increase R-loop formation in vitro, revealing their roles in R-loop dynamics and initiation.

1 citation

DNA methylationexperimental assay

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