Author

Asad M. Taherbhoy

Foghorn Therapeutics (United States)ORCID 0009-0009-8792-4188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alexis Khalil· 1 shared Anjanabha SahaiD· 1 shared Arthur Sands· 1 shared Austin Tenn-McClellaniD· 1 shared Bengi Turegun· 1 shared Brandon J. Bravo· 1 shared Brenna Sherbanee· 1 shared Chenbo WangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMolecular Biology

Alexis Khalil

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 24, 2026

Discovery and characterization of small molecule inhibitors of CBL-B that act as intramolecular glue to enhance T-cell anti-tumor activity

Stefan Gajewski, Asad M. Taherbhoy, Kathleen Boyle…·Frederick Cohen

1 citation

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Molecular BiologybioRxivPreprintAug 1, 2025

Structural and functional basis of PU.1-BAF interaction enables targeting of lineage-specific transcription

Dipti Sadalge, Jozlyn R. Clasman, Salih Topal…·Asad M. Taherbhoy

This paper identifies the structural basis of PU.1-BAF interaction and shows small molecules can disrupt it, offering a new therapeutic strategy for cancer.

2 citations

humanprotein structure

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Cell BiologybioRxivPreprintDec 18, 2023

Hijacking the transcriptional activation potential of the BAF complex via Induced Proximity

Lionel Chia, David L. Mayhew, Brenna Sherbanee…·Asad M. Taherbhoy

This study uses induced proximity to redirect BAF complexes to activate therapeutic genes, altering chromatin landscapes and identifying proliferation-suppressing genes.

2 citations

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