BioengineeringFrontiers in Genome EditingPeer-reviewed
Long Read Sequencing reveals transgene concatemerization and backbone integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes
Muhammad Waqas Luqman, Piroon Jenjaroenpun, Jessica Spathos…·Fabien Delerue
The paper uses long-read sequencing to analyze unintended on-target mutations in mouse zygotes edited with AAV-delivered CRISPR RNP complexes.
10 citations