Lars Matthias Ittner

This study identifies the lncRNA Dory as essential for female spatial memory and balance, with no effect in males, using CRISPR and RNA sequencing in mice.

The paper engineers a bacterial encapsulin into a nanoscaffold for controlled antigen display, demonstrating its utility in generating single- and multi-target nanovaccines for Alzheimer's disease.

The paper uses long-read sequencing to analyze unintended on-target mutations in mouse zygotes edited with AAV-delivered CRISPR RNP complexes.

This study shows that SARS-CoV-2 spike and orthoreovirus p15 proteins induce fusion between neurons and glial cells across species, leading to syncytia and organelle exchange.

The paper identifies differences in mitochondrial protein interaction profiles between wild-type and A147T polymorphism variants of TSPO in human glial cells.

The paper identifies cyclin F interactors using BioID and shows that ALS/FTD-associated cyclin F mutations disrupt paraspeckle protein homeostasis, particularly RBM14 levels in patient tissue.