SETD7-mediated lysine monomethylation is abundant on non-hyperphosphorylated nuclear Tau
Maria Bichmann, Nuria Prat Oriol, Ebru Ercan-Herbst, David C. Schöndorf, Borja Gomez Ramos, Vera Schwärzler, Marie Neu, Annabelle Schlüter, Xue Bing Wang, Liang Jin, Chenqi Hu, Yu Tian, Janina S. Ried, Per Haberkant, Laura Gasparini, Dagmar E. Ehrnhoefer
The paper identifies lysine monomethylation on Tau by SETD7 in human brain tissue and shows its association with nuclear Tau in a mouse model of tauopathy.
Molecular Neurodegeneration · Jul 2, 2021Peer-reviewedNeuroscience