Author

Lars Gruber

Technische Hochschule MannheimORCID 0009-0009-9955-1550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Carsten HopfiD· 2 shared Stefan SchmidtiD· 2 shared Thomas EnzleiniD· 2 shared Denis Abu SammouriD· 1 shared Florian KelleriD· 1 shared Gernot SchabbaueriD· 1 shared Huong Giang VoiD· 1 shared James Lucas CairnsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Carsten HopfORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 22, 2025

Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy

Lars Gruber, Stefan Schmidt, Thomas Enzlein…·Carsten Hopf

This paper introduces a method combining quantum cascade laser infrared imaging with mass spectrometry to improve molecular identification in spatial omics, achieving high-resolution lipidomics profiling.

35 citationstop 1%

mousespatial transcriptomics

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BiochemistryGigaSciencePeer-reviewedJan 1, 2025

A sulfatide-centered ultra-high resolution magnetic resonance MALDI imaging benchmark dataset for MS1-based lipid annotation tools

Lars Gruber, Stefan Schmidt, Thomas Enzlein, Carsten Hopf

The paper introduces two sulfatide-centered MR-MSI datasets for benchmarking lipid annotation tools, showing improved confidence in annotations using ultra-high-resolution data.

2 citations

mousespatial transcriptomics

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