Thomas Enzlein

This paper introduces a method combining quantum cascade laser infrared imaging with mass spectrometry to improve molecular identification in spatial omics, achieving high-resolution lipidomics profiling.

The paper introduces two sulfatide-centered MR-MSI datasets for benchmarking lipid annotation tools, showing improved confidence in annotations using ultra-high-resolution data.

The paper develops a multimodal imaging workflow to analyze A{beta} plaque microenvironments in AD mice using mass spectrometry, histology, and immunohistochemistry on a benchtop instrument.

This study develops a label-free MALDI-TOF mass spectrometry bioassay to assess complement-dependent cytotoxicity of Rituximab, identifying metabolite markers and demonstrating robust concentration-response characteristics.

The paper uses iSILK to track Aβ plaque aggregation dynamics in AD mouse models, identifying cortical deposition and structural heterogeneity in plaque composition.