Author

Stefan Schmidt

Technische Hochschule MannheimORCID 0000-0003-2896-3290Unclaimed ORCID profile · follow to get notified of new preprints

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Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Carsten HopfiD· 3 shared Thomas EnzleiniD· 2 shared Alexander Geisel· 1 shared Andrea Lewen· 1 shared Björn Fröhlich· 1 shared Christian Graf· 1 shared Daniel C. SéviniD· 1 shared James Lucas CairnsiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

Carsten HopfORCID

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3 papers

Recent·Most cited

BiochemistryGigaSciencePeer-reviewedJan 1, 2025

A sulfatide-centered ultra-high resolution magnetic resonance MALDI imaging benchmark dataset for MS1-based lipid annotation tools

Lars Gruber, Stefan Schmidt, Thomas Enzlein, Carsten Hopf

The paper introduces two sulfatide-centered MR-MSI datasets for benchmarking lipid annotation tools, showing improved confidence in annotations using ultra-high-resolution data.

2 citations

mousespatial transcriptomics

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BioinformaticsbioRxivPreprintOct 15, 2024

Fast Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers

James Lucas Cairns, Johanna Huber, Andrea Lewen…·Carsten Hopf

The paper introduces PRISM-MS, a method for fast single-cell MALDI imaging of low-mass metabolites, and demonstrates its application in analyzing metabolome changes in LPS-stimulated microglial cells.

1 citation

humanmouse

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BiochemistryScientific ReportsPeer-reviewedSep 13, 2024

Label-free Assessment of Complement-Dependent Cytotoxicity of Therapeutic Antibodies via a Whole-Cell MALDI Mass Spectrometry Bioassay

S. Schmidt, Alexander Geisel, Thomas Enzlein…·Carsten Hopf

This study develops a label-free MALDI-TOF mass spectrometry bioassay to assess complement-dependent cytotoxicity of Rituximab, identifying metabolite markers and demonstrating robust concentration-response characteristics.

2 citations

humanmetabolomics

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