VaccinesMolecular BiologyPeer-reviewed journal article
Virological traits of the SARS-CoV-2 BA.2.87.1 lineage
Lu ZhangiD, Alexandra Dopfer‐JablonkaiD, Inga NehlmeieriD, Amy Madeleine Kempf, Luise Graichen, Noemí Calderón Hampel, Anne CossmanniD, Metodi V. StankoviD, Gema Morillas RamosiD, Sebastian R. SchulziD, Hans‐Martin JäckiD, Georg M. N. BehrensiD, Stefan PöhlmanniD, Markus HoffmanniD
Abstract
The highly mutated SARS-CoV-2 BA.2.87.1 lineage was recently detected in South Africa, but its transmissibility is unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently dominating JN.1 variant. Acquisition of adaptive mutations might thus be needed for high transmissibility.
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