Inga Nehlmeier

Epidemiology and virological characteristics of the emerging SARS-CoV-2 variant PJ.2.1

The paper characterizes the epidemiology and virology of the SARS-CoV-2 variant PJ.2.1, finding it spreads mainly in older adults and shows increased ACE2 binding but not greater antibody evasion.

The conserved QTQTX motif in the SARS-CoV-2 spike protein is dispensable for cleavage and lung cell entry of the emerging variant BA.3.2

This study shows the QTQTX motif in BA.3.2 S protein is not required for cleavage or lung cell entry, which depends on TMPRSS2 instead.

Proteolytic processing of the Marburg virus glycoprotein depends on Sec616β and is required for cell entry

This paper identifies Sec61β as essential for proteolytic processing and cell entry of Marburg virus glycoprotein, unlike Ebola virus, and suggests Sec61 as a therapeutic target.

Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC

The paper characterizes the XEC SARS-CoV-2 lineage and evaluates the neutralization effect of JN.1 booster vaccination against KP.3.1.1 and XEC variants.

Virological traits of the SARS-CoV-2 BA.2.87.1 lineage

This study investigates the virological traits of the SARS-CoV-2 BA.2.87.1 lineage, finding it efficiently enters human cells but is more sensitive to antibody neutralization than JN.1.

SARS-CoV-2 variant B.1.617 is resistant to Bamlanivimab and evades antibodies induced by infection and vaccination

Increased lung cell entry of B.1.617.2 and evasion of antibodies induced by infection and BNT162b2 vaccination

This study shows that the B.1.617.2 variant of SARS-CoV-2 evades antibodies from infection and vaccination, increases lung cell entry, and enhances cell fusion.