bioRxivNeurosciencePreprint
BRAin INteractive Sequencing Analysis Tool (BRAIN-SAT); facilitating interactive transcriptome analyses (http://brainsat.eu/)
Marissa Lisa DubbelaariD, Maaike L. Brummer, M. Meijer, Bart J. L. EggeniD, H. W. G. M. BoddekeiD
Abstract
Over the last decade, a large number of glia transcriptome studies has been published. New technologies and platforms have been developed to allow access and interrogation of the published data. The increase in large transcriptomic data sets allows for innovative in silico analyses to address biological questions. Here we present BRAIN-SAT, the follow-up of our previous database GOAD, with several new features available on an interactive platform that enables access to recent, high quality bulk and single cell RNA-Seq data. The combination of several functions including gene searches, differential and quantitative expression analysis and a single cell expression analysis feature enables the exploration of published data sets at different levels. These different functionalities can be used for researchers and research companies in the neuroscience field to evaluate and visualize gene expression levels in a set of relevant publications. Here, we present a new platform with easy access to published gene expression studies for data exploration and gene of interest searches.
- organism: human
- organism: mouse
- assay: bulk RNA-seq
- assay: scRNA-seq
- research focus: database / resource
- research focus: gene regulatory network inference
- research focus: differential expression
- approach: statistical model
- Citations
- 2
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