Xu-Fei Du

NeuroPack: Advanced Learnable Packaging Toolkit Towards Ultra-High Compression Ratio for Volumetric Neuroimaging

NeuroPack compresses 3D neuroimaging data with high fidelity and ultra-high compression ratios using a hyperprior-driven deep learning toolkit.

An applicable and efficient retrograde monosynaptic circuit mapping tool for larval zebrafish

This paper develops an efficient method for retrograde monosynaptic tracing in larval zebrafish neural circuits using modified rabies viruses.

iBrAVE: a unified framework for 3D interactive and integrative analysis of brain atlas data across modalities and scales

iBrAVE integrates multimodal and multiscale brain atlas data across species, enabling interactive analysis of molecular, structural, and functional information.

Multi-level broad-yet-sparse input organization of LC-NE neurons revealed by multiplexed whole-brain EM reconstruction

The paper maps synaptic input architecture of LC-NE neurons in larval zebrafish, revealing broad-yet-sparse input organization across brain regions.

Multiple-level organizational logic of the locus coeruleus-norepinephrine system in structure and function

The paper reveals how locus coeruleus-norepinephrine neurons organize to regulate brain-wide neural dynamics through region-specific axon projections and synchronized firing.

A tectal reservoir implements adaptive visuomotor transformation via serotonergically coordinated push-pull-like mechanisms

The paper builds a biologically constrained spiking neural network of the zebrafish optic tectum to reveal how serotonergic systems and interneuron-type mechanisms enable adaptive visuomotor transformation.

Nervous system-wide single-cell morphology atlas of excitatory and inhibitory neurons in larval zebrafish

The paper creates a comprehensive atlas of larval zebrafish neuron morphology, including excitatory and inhibitory identities and connectivity patterns.

Super-Resolution Imaging of Fast Morphological Dynamics of Neurons in Behaving Animals

The paper develops a super-resolution microscopy technique to image neuronal morphology in behaving animals, revealing fast spinule dynamics and PSD-95 cluster correlations.

Ca2+ activity is required for injury-induced migration of microglia

This study shows that intracellular Ca2+ activity is necessary for microglia migration after brain injury in zebrafish.