Author

Erik Boddeke

University of CopenhagenORCID 0000-0002-5058-9648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Approach:statistical model· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2

Frequent Co-Authors

Bart J. L. EggeniD· 4 shared Marissa Lisa DubbelaariD· 3 shared Nieske Brouwer· 3 shared Emma GerritsiD· 2 shared Laura KrachtiD· 2 shared Susanne M. KooistraiD· 2 shared A. Geleijnse· 1 shared A.-M. van Dam· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Bart J. L. EggenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epigenetic regulation of innate immune memory in microglia

Xiaoming Zhang, Laura Kracht, Antônio Marcondes Lerário, Marissa Lisa Dubbelaar, Nieske Brouwer, Evelyn M. Wesseling, Erik Boddeke, Bart J. L. Eggen, Susanne M. Kooistra

The paper investigates how epigenetic changes in microglia influence their response to inflammatory and genotoxic stress, identifying distinct gene networks and functional phenotypes.

Journal of Neuroinflammation · May 14, 2022Peer-reviewedNeuroscience

Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue

Astrid M. Alsema, Qiong Jiang, Laura Kracht, Emma Gerrits, Marissa Lisa Dubbelaar, Anneke Miedema, Nieske Brouwer, Elly M. Hol, Jinte Middeldorp, Roland E. van Dijk, Maya E. Woodbury, Astrid Wachter, Hualin Simon Xi, Thomas Möller, Knut Biber, , Bart J. L. Eggen

The paper profiles microglia transcriptomes in AD donors and non-demented elderly using bulk and single-cell RNA sequencing, finding no significant differences in gene expression or subcluster composition.

Frontiers in Molecular Neuroscience · Oct 28, 2020Peer-reviewedNeuroscience

Distinct gene expression profiles in leukocortical demyelinated white and grey matter areas of Multiple Sclerosis patients

Thecla A. van Wageningen, Emma Gerrits, A. Geleijnse, Nieske Brouwer, Jeroen J.G. Geurts, Bart J. L. Eggen, H. W. G. M. Boddeke, A.-M. van Dam

The paper compares gene expression profiles of demyelinated white and grey matter in MS patients, finding minimal overlap and distinct glial cell signatures.

bioRxiv · Jun 3, 2020 · PreprintNeuroscience

BRAin INteractive Sequencing Analysis Tool (BRAIN-SAT); facilitating interactive transcriptome analyses (http://brainsat.eu/)

Marissa Lisa Dubbelaar, Maaike L. Brummer, M. Meijer, Bart J. L. Eggen, H. W. G. M. Boddeke

BRAIN-SAT provides an interactive platform for exploring bulk and single-cell RNA-Seq data from neuroscience studies, enabling gene expression analysis and visualization.

bioRxiv · Aug 30, 2019 · PreprintNeuroscience