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MicrobiologybioRxiv

Disinfection of Methicillin-Resistant Staphylococcus aureus, Vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system

R. M. Mariita, R. V. Randive

Abstract

Healthcare-associated infections (HAIs) are a major burden in healthcare systems. In this study, UVC LEDs emitting radiation from 260-270 nm were evaluated for effectiveness in reducing methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and Acinetobacter baumannii. The array has four WD LEDs, each with 70mW placed at 7cm from test organism. With 11.76 mJ/cm2, the study obtained 99.99% reduction (log10 reduction factor of 4) against MRSA and VRE. For A. baumannii, 9 mJ/cm2 obtained 99.999% reduction (log10 reduction factor of 5). These results present scientific evidence on how effective UVC LEDs can be used in the fight against HAIs.

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