canvasXpress: A versatile interactive high-resolution scientific multi-panel visualization toolkit

To the Editor: CanvasXpress (https://canvasxpress.org) was developed as the core visualization component for bioinformatics and systems biology analysis at Bristol-Myers Squibb and further enhanced by scientists around the world and served as a key visualization engine for many popular bioinformatics tools1,2,3,4,5,6. It offers a rich set of interactive plots to display scientific and genomics data, such as oncoprint of cancer mutations, heatmap, 3D scatter, violin, radar, and profile plots (Figure 1, canvasXpress plots arranged by canvasDesigner https://baohongz.github.io/canvasDesigner). Recently, the reproducibility and usability of the package in real world bioinformatics and clinical use cases have been improved significantly witnessed by continuous add-on features and wide adoption of the toolkit in the scientific communities. Furthermore, It is the first noteworthy package harmonizing real time interactive exploring and analyzing of big data, full-fledged customizing of look-n-feel, and producing multi-panel publication-ready figures in PDF format simultaneously.\n\nO_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=84 SRC=\"FIGDIR/small/186213_fig1.gif\" ALT=\"Figure 1\">\nView larger version (36K):\norg.highwire.dtl.DTLVardef@1d8392borg.highwire.dtl.DTLVardef@916a49org.highwire.dtl.DTLVardef@d90b05org.highwire.dtl.DTLVardef@162a8fc_HPS_FORMAT_FIGEXP M_FIG O_FLOATNOFigure 1.C_FLOATNO Versatile plots generated by canvasXpress. A) Oncoprint of cancer mutations; B) Gene expression heatmap with comprehensive annotations; C) 3D scatter plot; D) Violin plot; E) Radar plot with annotations; F) Profile plot of gene expression.\n\nC_FIG