Nanoparticle-in-Microparticle Oral Delivery System Based on Drug-Loaded Polymeric Micelles
Hen Moshe Halamish, Roni Sverdlov ArziiD, Alejandro SosnikiD
Abstract
This work develops and characterises a hierachichal oral drug delivery system based on the microencapsulation of drug-loaded amphiphilic nanogels within a mucoadhesive alginate/chitosan shell. Results show a more controlled release and a statistically significant oral half-life with respect to the free drug.
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