Musical Insights into Protein Sequences and Functions via NMR Data

Abstract

This study explores an innovative technique for transforming rhythmic patterns found in nature into music, with a focus on protein sequences. For the past twenty years, various strategies have been developed for musical translation of biological sequences. This research presents a groundbreaking approach where music is derived from protein nano-scale structures using the atomic frequencies of amino acids extracted from NMR experiments. Each amino acid is assigned a unique musical note and duration, determined by its 13CNMR spectrum and relaxation period. Applying this method, music was composed from different protein sequences, including homologue {beta}-globin, where a set theory-based comparative analysis was conducted. This novel approach opens up a new auditory dimension for understanding protein functions.