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BioinformaticsBioinformatics
Peer-reviewed journal article

mirtronDB: a mirtron knowledge base

Bruno Henrique Ribeiro da FonsecaiD, Douglas Silva DominguesiD, Alexandre Rossi PaschoaliD

Abstract

MotivationMirtrons are originated from short introns with atypical cleavage from the miRNA canonical pathway by using the splicing mechanism. Several studies describe mirtrons in chordates, invertebrates and plants but in the current literature there is no repository that centralizes and organizes these public and available data. To fill this gap, we created the first knowledge database dedicated to mirtron, called mirtronDB, available at http://mirtrondb.cp.utfpr.edu.br/. MirtronDB has a total of 1,407 mirtron precursors and 2,426 mirtron mature sequences in 18 species.\n\nResultsThrough a user-friendly interface, users can browse and search mirtrons by organism, organism group, type and name. MirtronDB is a specialized resource to explore mirtrons and their regulations, providing free, user-friendly access to knowledge on mirtron data.\n\nAvailabilityMirtronDB is available at http://mirtrondb.cp.utfpr.edu.br/.\n\nContactpaschoal@utfpr.edu.br\n\nSupplementary informationSupplementary data are available.

PDFDOI

02 /Specification & Classification

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