Giovanni Nigita

This study uses a multi-omics approach to show miR-411ed enhances Osimertinib efficacy in TKI-resistant NSCLC by targeting STAT3 and altering interferon and ERK/MAPK pathways.

This study investigates how METTL3 regulates RNGTT expression and activity, finding that METTL3 knockdown destabilizes RNGTT mRNA and reduces protein expression, with downstream effects on ribosomal protein capping and mTOR pathway disruption.

This study shows KDM2B promotes ribosome biogenesis by enhancing transcription of ribosome-related genes and affects mRNA translation unequally based on mRNA features.

MiREDiBase is a manually curated database of validated and putative miRNA editing events, including 3,059 sites from 626 pre-miRNAs in humans and three primates.